https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Remediation of poly- and perfluoroalkyl substances (PFAS) contaminated soils - to mobilize or to immobilize or to degrade? https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39613 Wed 10 Aug 2022 11:41:40 AEST ]]> Exposure to perfluorooctanesulfonate (PFOS) but not perflurorooctanoic acid (PFOA) at ppb concentration induces chronic toxicity in Daphnia carinata https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46333 Daphnia carinata) using a battery of comprehensive toxicity tests, including a 48 h acute and a 21-day chronic assays. The survival, growth, and reproduction of D. carinata were monitored over a 21-day life cycle. PFOS exhibited higher toxicity than PFOA. The 48 h LC50 values (confidence interval) based on acute toxicity for PFOA and PFOS were 78.2 (54.9–105) mg L−1 and 8.8 (6.4–11.6) mg L−1, respectively. Chronic exposure to PFOS for 21 days displayed mortality and reproductive defects in D. carinata at a concentration as low as 0.001 mg L−1. Genotoxicity assessment using comet assay revealed that exposure for 96 h to PFOS at 1 and 10.0 mg L−1 significantly damaged the organism's genetic makeup. The results of this study have great implications for risk assessment of PFOS and PFOA in aquatic ecosystems, given the potential of PFOS to pose a risk to Daphnia even at lower concentrations (1 μg L−1).]]> Tue 15 Nov 2022 12:49:03 AEDT ]]> Prenatal phthalate exposure in relation to placental corticotropin releasing hormone (pCRH) in the CANDLE cohort https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45377 Thu 27 Oct 2022 16:12:31 AEDT ]]> Prenatal polycyclic aromatic hydrocarbon (PAH) exposure in relation to placental corticotropin releasing hormone (pCRH) in the CANDLE pregnancy cohort https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49847 Mon 05 Jun 2023 15:51:30 AEST ]]> Per- and polyfluoroalkyl substances (PFAS) in commercial composts, garden soils, and potting mixes of Australia https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47455 Fri 20 Jan 2023 17:38:34 AEDT ]]> Uptake, accumulation, and toxicity of per- and polyfluoroalkyl substances in Allium cepa grown in soils amended with biosolids https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50286 Fri 14 Jul 2023 09:21:20 AEST ]]> Evaluation of cyto-genotoxicity of Perfluorooctane Sulfonate (PFOS) to Allium cepa https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44045 Allium cepa root meristem cells. The A. cepa root tips were exposed to 6 different concentrations (1–100 mg L−1) of PFOS for 48 h. Reduction in mitotic index and chromosomal aberrations was measured as genotoxic endpoints in meristematic root cells. Exposure to PFOS significantly affected cell division by reducing the miotic index at higher concentrations (>10 mg L−1). The median effect concentration of PFOS to elicit cytotoxicity based on the mitotic index was 43.2 mg L−1. Exposure to PFOS significantly increased chromosomal aberrations at concentrations >25 mg L−1. The common aberrations were micronuclei, vagrant cells, and multipolar anaphase. The alkaline comet assay revealed a genotoxic potential of PFOS with increased tail DNA percentage at concentrations >25 mg L−1. To our knowledge, this is the first study to report the cyto-genotoxic potential of PFOS in higher plants.]]> Fri 07 Oct 2022 14:28:51 AEDT ]]>